Our Extended Family of Portfolio Companies

Investing in transformational ideas and entrepreneurial grit to solve major unmet needs in patient care

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410 Medical develops innovative resuscitation technologies for emergency and critical care.

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Aer Therapeutics is a clinical-stage biopharmaceutical company developing first-in-class inhaled therapies that target mucus obstruction in chronic lung diseases.

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Altis has developed a patent-pending stem cell technology recreating the human intestinal epithelium for compound screening and microbiome research.

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AN2 Therapeutics is a clinical-stage biotech company advancing novel small molecule therapeutics.

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Developer of scientific data management software designed to enhance workplace collaboration. Acquired by PerkinElmer (NYS: PKI) in March 2011.

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AtaCor Medical is developing next-generation cardiac rhythm management systems

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Providing in-home primary care for seniors with complex conditions, especially those with dementia

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Atsena Therapeutics is a clinical-stage gene therapy company focused on reversing or preventing blindness from inherited retinal diseases

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Avivomed is a Minneapolis-based medical device company developing next-generation neuromodulation therapies

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Axonis Therapeutics is a clinical-stage biotechnology company developing first-in-class small molecule therapies that target KCC2

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Ed-tech platform that pairs high achieving, under-resourced students with mentors to guide them to successful career outcomes

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Their clinical research software accelerates timelines by automating multiple high impact processes.

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Bivarus is a healthcare IT company that has developed an elegant and efficient patient survey platform. Acquired by Press Ganey Associates in January 2018.

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Boomerang Medical is a bioelectronic medicine company developing neuromodulation technologies to treat autoimmune diseases

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Boston Immune Technologies & Therapeutics is a clinical-stage biotechnology company developing a novel class of antagonist antibodies

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Carallel is a digital health company that provides personalized guidance, expert support, and technology tools

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Cardiosense combines multimodal wearable sensors with AI to noninvasively detect early signs of cardiac disease and guide personalized therapy.

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Clearside Biomedical is a biopharmaceutical company focused on revolutionizing treatment for sight-threatening back-of-the-eye diseases. IPO in June, 2016 (NASDAQ:CLSD).

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Clinipace is a clinical research organization whose services are enhanced by a proprietary on-demand software platform and clinical research services. Acquired by dMed in April 2021.

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Developer of an online platform for clinical payments. Acquired by BioClinica on January 19, 2016.

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Code Bio is a preclinical stage company developing novel genetic medicines.

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Contego Medical develops integrated medical devices for revascularization procedures

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CREATE Medicines is a clinical-stage biotechnology company pioneering a new class of in vivo immune programming therapies

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Curoverse developed a genomic and biomedical computing platform. Acquired by Veritas Genetics in August 2017.

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CVRx develops an implantable system that delivers baroreflex activation therapy. IPO in June 2021 (NASDAQ: CVRX).

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Developer of a technology designed to extract highly sensitive nucleic acid quantification. Acquired by Bio-Rad 2021

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Elligo Health Research is a healthcare-enabling research organization that integrates clinical trials directly into routine patient care

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Developer of a system to enhance embolic cerebral protection. Acquired by Edwards Lifesciences (NYSE: EW) in March 2011.

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Endogenex is a clinical-stage medical technology company developing a novel, minimally invasive endoscopic procedure for people with type 2 diabetes.

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Entegrion develops point-of-care hemostasis solutions centered on its Viscoelastic Coagulation Monitor (VCM)

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G1 Therapeutics, Inc. is a commercial-stage biopharmaceutical company. IPO in May 2017 (NASDAQ: GTHX) Acquired by Pharmacosmos in 2024

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GeneCentric’s mission is to address the urgent unmet need in precision oncology for better biomarkers and to bring these biomarkers to liquid biopsies.

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GoCheck Kids provides a smartphone-based pediatric vision and hearing screening platform

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Gozio Health is a digital health company that provides a customizable, mobile engagement platform for health systems

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Graybug Vision, Inc. was a clinical-stage ophthalmology company developing sustained-release therapies. IPO in September 2020 (NASDAQ: GRAY).

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HistoSonics, Inc. is pioneering a novel, non-invasive therapeutic platform based on histotripsy. Acquired by Bezos Expeditions, Wellington K5 Global 2025

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Huma.AI is a life sciences–focused generative AI company that provides a secure knowledge platform

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MMvention Therapeutix, Inc. is an early-stage biotechnology company focused on discovering and developing novel oral small-molecule therapeutics

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Engages patients and families in a personalized way to initiate discussions on end-of-life care planning. Acquired by Aledade in January 2022.

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iVEAcare is developing next-generation neuromodulation therapies using advanced implantable devices and software

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Founded by pediatricians, developing medical content in an educational format embraced by children. Acquired by Falfurrias 2024

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Kymera Therapeutics, Inc. is a clinical-stage biotechnology company pioneering targeted protein degradation. IPO in August 2020 (NASDAQ: KYMR).

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Developer of innovative neurodegeneration small-molecules intended to establish a platform for novel drug discovery.Acquired by Bial in October 2020.

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Provider of patient experience platform designed to facilitate the relationship between physicians and patients. Acquired by NextGen 2019

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Mercy BioAnalytics is a biotechnology company developing blood-based tests for the early detection of cancer

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Operator of a biopharmaceutical agency intended to offer drugs for the treatment of diabetes and other metabolic disorders.

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Developer of staffing, communication and schedule management tools designed to modernize staffing processes. Acquired by HealthStream 2020

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The Company’s lead product candidate, PB2452, is a novel reversal agent for the antiplatelet drug ticagrelor. IPO in October, 2018 (NASDAQ:PHAS)

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Perfuse Therapeutics is a clinical-stage biopharmaceutical company developing first-in-class therapies to improve retinal blood flow and treat ischemia-driven eye diseases.

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Developer of a molecular diagnostics technology designed to dramatically reduce time to results in microbiology.

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Qpex Biopharma is a clinical-stage biopharmaceutical company developing novel anti-infective therapies. Acquired by Shionogi 2023

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RapidPulse is a medical device company developing an innovative, minimally invasive vascular system for treating acute ischemic stroke.

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Ribometrix is a biotechnology company pioneering a new class of small-molecule therapeutics that directly target the three-dimensional structures of RNA to modulate disease biology.

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Rodin Therapeutics was a biotechnology company focused on discovering and developing first-in-class small molecule therapeutics. Acquired by ALKS in Nov 2019

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Rx Redefined is a healthcare technology company that provides a compliance-focused platform

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SafeRide Health is a healthcare technology and services company that improves access to care by coordinating non-emergency medical transportation for vulnerable populations.

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Shattuck Labs is a clinical-stage biotechnology company advancing novel biologic medicines for inflammatory and immune-mediated diseases. IPO in October 2020 (NASDAQ: STTK)

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Standard Bariatrics is a medical device company focused on advancing bariatric surgery.

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Stridebio is developing engineered viral vectors for gene therapy. Acquired by Ginkgo Bioworks 2023

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Sensorium Therapeutics is a clinical-stage biotechnology company developing next-generation brain and mental health medicines.

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Synaptrix is developing a first-in-kind, drug-free neuromodulation therapy for post-operative pain

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Ten63 Therapeutics is a computational drug discovery company leveraging its proprietary AI- and physics-based platform to design novel therapeutics

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Trefoil Therapeutics is a clinical-stage biotechnology company developing regenerative therapies to restore vision for people with corneal diseases.

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Tune Therapeutics is a biotechnology innovator advancing a new class of epi-therapeutic medicines

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The company’s lead drug has potential to be a game-changer in the treatment of HITT. Acquired by Cadrenal Therapeutics 2025

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Viamet Pharmaceuticals is a biotechnology company. Acquired by NovaQuest Capital Management in January 2018.

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Vigil Neuroscience is a clinical-stage biotechnology company. IPO in January 2022 (NASDAQ: VIGL). Acquired by Sanofi in 2025.

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Vircho is a healthcare technology company that connects healthcare organizations with community-based social services

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Wesper is a digital health company developing an FDA-cleared, at-home sleep testing platform that delivers clinical-grade diagnostics for sleep disorders

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Wildflower Health is a digital health company focused on women’s and maternal health

“It is not the critic who counts: not the man who points out how the strong man stumbles or where the doer of deeds could have done better. The credit belongs to the man who is actually in the arena, whose face is marred by dust and sweat and blood, who strives valiantly, who errs and comes up short again and again, because there is no effort without error or shortcoming, but who knows the great enthusiasms, the great devotions, who spends himself in a worthy cause; who, at the best, knows, in the end, the triumph of high achievement, and who, at the worst, if he fails, at least he fails while daring greatly, so that his place shall never be with those cold and timid souls who knew neither victory nor defeat.”


Theodore Roosevelt
Speech at the Sorbonne, Paris, April 23, 1910