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PhaseBio is a biopharmaceutical company built around the proprietary application of elastin-like polypeptides (ELP's) for protein purification and drug delivery. Based upon over a decade of research by Ashutosh Chilkoti of Duke University, PhaseBio promises to bring the first new technology for protein purification since column chromatography, thereby significantly reducing the time and cost of downstream processes in biologics manufacturing. PhaseBio's drug programs in drug delivery improve the delivery characteristics of pharmaceutical products by extending half-life and localizing delivery to target tissues. PhaseBio was featured in the May 5, 2008 issue of BioCentury.
Viamet Pharmaceuticals is a drug discovery company that is developing novel therapeutics that target metalloenzymes. Viamet's scientific foundation is based on a growing understanding of the critical role of metals in the activity of key biological targets important in various disease processes, including infectious disease and inflammation.
Clinipace is a clinical research software company providing a single, integrated data capture and study management platform for clinical trials, post-approval research, and registries. Its customers include pharmaceutical companies, medical device companies, biotech companies, CROs, and academic medical centers. Clinpace's platform, called TEMPO, is delivered via a web-based, on-demand architecture that streamlines the clinical research process by eliminating the integration headaches associated with multiple platforms, reducing project efforts and costs from startup to conclusion, and empowering project stakeholders to make informed real-time decisions regarding their research.
ArtusLabs is a technology company that enables scientific data management and workplace collaboration for research-driven entities such as biotech companies, pharmaceutical companies, and academic institutes and laboratories. Blending together the management of unstructured information and insights with social networking, personal publication, and refined data mining, ArtusLabs can significantly enhance internal and external research communication and research management.
SpineWorks Medical is an early stage medical device company dedicated to the design, development and successful commercialization of minimally-invasive products for spinal surgery. The company currently has products under review by the FDA and anticipates having a CE Marked product cleared for European commercialization by the end of calendar year 2008.
Respirics is a respiratory drug company focused on development and delivery of powdered formulations of important respiratory medications. The company's Accu-Breathe delivery device is the first of its kind to enable the dispensing of powdered drug as the patient inhales, improving patient compliance and therapy. Respiric's lead program is Accu-30 Albuterol, the first powdered form of albuterol in clinical development in the United States.
Synthematix (now Symyx Technologies, Inc. - SMMX) is focused on developing and deploying software solutions for discovery and medicinal chemists. In April 2005, Synthematix was acquired by Symyx Technologies for $13MM cash (giving HVP a return multiple of 5.5X).
Based upon technology from UNC and East Carolina University that was funded by over a decade of Department of Navy funding, Entegrion is developing hemostatic technologies for wound management, tissue repair, and control of hemorrhage. The company's lead product (Stasilon-FR, formerly AlphaBandage) is FDA approved for use as an external hemostatic bandage.
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